I'm a Lean Mass Hyper-Responder (LMHR) Now - You?

Turning Off My LMHR
@Pablo
@alarmguy
I've decided to start adding back some more carbs to my diet (Paleo/Caveman) which I believe will change my lipid #s back to where they were prior to last December when I wasn't a LMHR. I'll do a blood test in a month or two to see what's going on. And I'll keep track of my ketones to see where they land.

If I see a BG spike above 140 mg/dL I'll back off the carb quanity a bit.

So far so good. Yesterday I included 1 cup (75 grams) of Millet. So as to lessen BG spike I mixed the millet (carbs) in with 1st meal course made up of fat & protein. Second course was about 1+ cups (75-100 grams) of baked then chilled seasoned sweet potatoe chunks that I dipped in 5% whole milk yogart.

Baked then chilled w/skin sweet potato has a low to moderate (7-10) glycemic load.

Milet has a high (51) glycemic load. Portion control and including it with fat is key for BG control.

5/7/26
Glucose = 120 mg/dL at 5 pm 1 hr after meal with Millet & Sweet potatoes.
Glucose = 133 mg/dL at 5:30 pm 1.5 hrs after meal with Millet & Sweet potatoes.
Glucose = 111 mg/dL at 6 pm 2 hrs after meal with Millet & Sweet potatoes.

Your results may vary.

 
Turning Off My LMHR
@Pablo
@alarmguy
I've decided to start adding back some more carbs to my diet (Paleo/Caveman) which I believe will change my lipid #s back to where they were prior to last December when I wasn't a LMHR. I'll do a blood test in a month or two to see what's going on. And I'll keep track of my ketones to see where they land.

If I see a BG spike above 140 mg/dL I'll back off the carb quanity a bit.

So far so good. Yesterday I included 1 cup (75 grams) of Millet. So as to lessen BG spike I mixed the millet (carbs) in with 1st meal course made up of fat & protein. Second course was about 1+ cups (75-100 grams) of baked then chilled seasoned sweet potatoe chunks that I dipped in 5% whole milk yogart.

Baked then chilled w/skin sweet potato has a low to moderate (7-10) glycemic load.

Milet has a high (51) glycemic load. Portion control and including it with fat is key for BG control.

5/7/26
Glucose = 120 mg/dL at 5 pm 1 hr after meal with Millet & Sweet potatoes.
Glucose = 133 mg/dL at 5:30 pm 1.5 hrs after meal with Millet & Sweet potatoes.
Glucose = 111 mg/dL at 6 pm 2 hrs after meal with Millet & Sweet potatoes.

Your results may vary.

Interested... I'm curious how this will go for you. I'm wondering if you will have a period of adaptation since you are fat adapted and if you will have higher peaks for a while until you reach a new equalibrium?
 
Interested... I'm curious how this will go for you. I'm wondering if you will have a period of adaptation since you are fat adapted and if you will have higher peaks for a while until you reach a new equalibrium?
me too ?

Ketones were still at 1.6 mmol/L before my meal today, so yesterdays carbs didn't "instantly" take me out of nutritional ketosis :)
 
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The following is info from the staycuriousmetabolism.substack.com I have a paid subscription too.

When Nick Norwitz MD, PhD, was 23 (7 yrs ago), he adopted a low-carbohydrate ketogenic diet to treat my ulcerative colitis. It worked—miraculously. His symptoms disappeared. His disease went into complete remission. But he became a "Lean Mas Hyper Responder (LMHR)".

By eliminating carbohydrates, his cholesterol, especially his LDL “bad” cholesterol, skyrocketed.
His total cholesterol breached 700 mg/dl. His LDL hit 574 mg/dl.
He ignored the doctors request to take steps to lower his cholesterol.

Recently he underwent a coronary CT angiography including an expert interpretation and AI-guided quantification.

After nearly seven years with a total cholesterol over 700 mg/dl, the total quantified plaque in my arteries—calcified and non-calcified—is zero, as in 0 mm3.

As has been said and shown many many times, "cholesterol is associated" with CVD and "not causial".

@Pablo
@alarmguy

Here is a pic of his total plaque summary.
Total Plaque Summary.webp
 
I'm trying to figure out how to do a screen shot of my heart/arteries since I have thousands of pics/images/????? whatever they're called like the above that came with my CCTA report.
I could tell you on a Mac or iPhone but not Windows. Been out of that world for so long now. But yeah, you got to find out of all the photo's which one you want to share. Been there on CT scans and Echo grams. Would love to see some.

As for Nick Norwitz I can't say for sure if it was me at 23 years old then got imaging at 30 I would have any plaque. I think that would be hard to say. I do think once vessels get damaged and that nice silky smooth lining of the arteries turns into a coarse sandpaper at that point it might provide the surface for Cholesterol to stick. Kind of like sanding plastic :) I suspect if he gets to 50+ it may be an issue. I have no clue.
For those that already have plaque for me personally I'll do a min statin.

Ps, Im in a grumpy mood. 29 hours into a 48 hour water fast! I watched my wife have a slice of pizza tonight and I forgot what else, much on some peanuts, go shopping in the supermarket (we just bought fruits and veggies) but boy everything looks good. Now Monday night at 10PM EST I am so looking forward to going to sleep in an hour so I can wake up for Tuesday and then roughly 8 or 9 more hours to go *LOL*
 
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Here's the open access article: https://www.mdpi.com/2079-9721/14/5/168

*Important note: The paper documenting this case has already undergone peer-review.

  • This will be the ‘doi’ link when the paper is live: https://doi.org/10.3390/diseases14050168
  • Once you can click on this link and it takes you to the paper, please share that link widely to socials, especially X (formerly Twitter) with a comment. That helps boost the paper in the tracking system.
  • If you really want to help out, check back on Friday to test the link and share it.
 
here is a panel discussion with members of the cast from the movie "The Cholesterol Code" talking about Keto etc and how it changed their lives:

I happened to look up that documentary just the other night. I thought it was part of my steaming services, it kind of is but right now you have to pay to view it. Not that it's a big deal but I havent because I never know if I will have the time to finish it. VS if it's free. I can go back to it any day.
 
Here's the open access article: https://www.mdpi.com/2079-9721/14/5/168

*Important note: The paper documenting this case has already undergone peer-review.

  • This will be the ‘doi’ link when the paper is live: https://doi.org/10.3390/diseases14050168
  • Once you can click on this link and it takes you to the paper, please share that link widely to socials, especially X (formerly Twitter) with a comment. That helps boost the paper in the tracking system.
  • If you really want to help out, check back on Friday to test the link and share it.
The link works. I do 100% believe this took place and others like it but it does not help me since I already have plaque and most likely have for decades. It's too late for me, so the question is ..... and the answer is .... I dont know. :unsure: I have to stay with my interpretation, along with what I learn and input from traditional specialists

His insulin was nice and low, mine was 11/ I also would have liked to know what is LIPO a was. Being they spoke of his dad.
Ps. 40 hours into a water fast so far.
 
Insulin sensitivity is #1 in my metabolic journey.

My sources indicate that the sweet spot for LDL cholesterol and all-cause mortality is 150 mg/dL. The graph for this is U shaped. Low and high increases risk of death. So, for now my goal

My imaging test results over the last yr indicate that I have mild/minimal 15-20% stenosis from atherosclerotic plaque localized at a upper point of my LAD artery only.

Is my plaque burden growing? Does plaque beget plaque? Only time and image testing will tell.

6 mths ago when I lowered my carb intake from 150ish grams/day (Paleo/Caveman diet) to <20ish grams of carbs per day I became a LMHR. My LDL jumped from 150ish to mid 200s.

So to bring back down to around 150 mg/dL I started adding back some healthy carbs. All my other metabolic markers/systems must remain healthy or I'll go back to <20 grams/day.

Your results may vary :)
 
Insulin sensitivity is #1 in my metabolic journey.

My sources indicate that the sweet spot for LDL cholesterol and all-cause mortality is 150 mg/dL. The graph for this is U shaped. Low and high increases risk of death. So, for now my goal

My imaging test results over the last yr indicate that I have mild/minimal 15-20% stenosis from atherosclerotic plaque localized at a upper point of my LAD artery only.

Is my plaque burden growing? Does plaque beget plaque? Only time and image testing will tell.

6 mths ago when I lowered my carb intake from 150ish grams/day (Paleo/Caveman diet) to <20ish grams of carbs per day I became a LMHR. My LDL jumped from 150ish to mid 200s.

So to bring back down to around 150 mg/dL I started adding back some healthy carbs. All my other metabolic markers/systems must remain healthy or I'll go back to <20 grams/day.

Your results may vary :)
Agree, insulin sensitivity
This is the area I’m getting confused.
Isn’t the two hour glucose test the ultimate in sensitivity/resistance?

What about fasting insulin from what I understand there is no standard but I see more doctors saying in the area of 2 versus doctors I think maybe Bickman claiming 8 for fasting insulin.
Some also say going to 100 for fasting insulin is silly and should be 70 to 90 range as the ultimate

I also read even though the standard is A1c of 5.7 is prediabetic they think it’s ridiculous that 5.6 isn’t being is only 1/10 away and even 5.3 they seem to stress if you really want to be in the clear it should be 5.0 or under.
Meaning, how do you tell somebody at 5.7 you prediabetic but at 5.6 you’re not and even at 5.3 does that really mean you’re healthy?

Yeah, I could be wrong but I think healthy carbs from the earth unaltered (except for genetics) is just that. For me that would be fruit though we know there’s a lot of sweet fruit you got me

Ps. 48 hours passed with just water and I had my meal tonight. Robust salad, protein drink probably a few too many walnuts. I could not resist the half of slice of pizza that was in my refrigerator.
Sent my blood sugar up to exactly 140, I was at 79 right before dinner. It’s dropping quick but what can I say? I’m human in that half slice was screaming to me to eat.

I kept the fast at 48 hours. After last week, I didn’t want to be too concerned about ketones.
I tested ketones before dinner and as best as I could tell, I was around four. Maybe once I’m down to my proper weight and have a fasting schedule set. I’ll get a real meter but right now. I don’t want to keep sticking my finger like six times a day. Lol

As mentioned, it’s tricky with the cell phone camera altering brightness color temperature, but this is a pretty fair representation that I took right before dinner

IMG_8219.webp


It takes me so long to make posts on my iPhone. I absolutely hate Apple speech to text. I love their devices, but … I don’t know with all this AI talk get my freaking phone to figure out what I’m saying🫤
 
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Agree, insulin sensitivity
This is the area I’m getting confused.
Isn’t the two hour glucose test the ultimate in sensitivity/resistance?

What about fasting insulin from what I understand there is no standard but I see more doctors saying in the area of 2 versus doctors I think maybe Bickman claiming 8 for fasting insulin.
Some also say going to 100 for fasting insulin is silly and should be 70 to 90 range as the ultimate
Bikman and most of the other doctors I pay attention to say fasting insulin below 6.0 UIU/ML is healthy. Mine was 2.0 UIU/ML when I tested it a couple of mths ago :)
but,
when I check my fasting glucose (remember my OMAD meal eatin by 3 pm everyday) in the morning between 6 to 10 am BG its usually 100 to 109 mg/dL, rarely in the 90s.
I also read even though the standard is A1c of 5.7 is prediabetic they think it’s ridiculous that 5.6 isn’t being is only 1/10 away and even 5.3 they seem to stress if you really want to be in the clear it should be 5.0 or under.
Meaning, how do you tell somebody at 5.7 you prediabetic but at 5.6 you’re not and even at 5.3 does that really mean you’re healthy?
Medical powers that be feel the need to draw a line in the sand.

I'm no rocket scientist but even I know there isn't much difference between 5.6 & 5.7
Yeah, I could be wrong but I think healthy carbs from the earth unaltered (except for genetics) is just that. For me that would be fruit though we know there’s a lot of sweet fruit you got me
Man has messed with some of our fruit, making it have a lot more sugar than it originally had. Example = apples, they use to be bitter.
 
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