"Stage 0" is often talked about before modifying a car/truck. It's the same thing I do when I induct a new vehicle (well...new to me, but used) into the fleet: baseline everything. New fluids/filters (including coolant if more than a few years old), clean TB, intake and injectors, new plugs, and ignition parts (if applicable), new accessory belt and even timing belt (again, if applicable), then I know where I am starting before driving and/or modifying said vehicle. Unless you've got all the history on this truck, you might consider starting there.
Frankly, I did very little maintenance to my Expedition (a 2000 4WD with the 5.4 and tow package) because it was the one vehicle that I've ever bought new. It rewarded my "by the book" maintenance with complete reliability. Not the best MPG, but it started and ran every time, including at -25 degrees in Vermont.
The ex kept it in the divorce, and junked it 2 years later when it was still young, 8 years old, 90K on it...I've bought cars older than that...but that's another story...