It's as clean or as messy as you want to make it. I've employed drain valves on all of my vehicles for several years now. No wrenches. No stripped drain plugs. No having hot oil running all over your hands.
No dropping the drain plug into the oil, and having to fish it out. As far as filters, some are easier to change than others. Spin on filters, (which all my vehicles have), are usually easier, and far less messy than a lot of the cartridge types.
But overall it not that bad of a job. Besides, at my age my hands are so dry and wrinkled, getting a little oil on them actually helps.