I have an Empire Blue Flame 20k btu ventless heater and I use it to heat my whole 1000sq ft ranch house in Central Illinois. Been using it for 4 years now. Many said I would be dead by now.

My outside 500 gallon propane tank has two regulators, ~5 psi from the tank to the house and a regular ~1 psi regulator for the gas going into the house.
Never had a problem with vaporization and we were down to a -24F and a couple other -20F nights in the last two weeks.
You need constant exhaust ventilation in the house unless you have a very drafty house. I use a bath fan exhaust and it runs 24/7.
CO is not a problem as long as you have enough O2 in the house. The flames will yellow as the O2 content goes down. The O2 content will go down because of the CO2 produced. I would advise getting a CO2 meter to monitor the air and for me you need to keep it below 4k ppm.
My CO meter has never made a peep.
It has a fan on it and it runs all the time. But I also use a box fan to blow the cool air out of the space I am in at the time.