I'm running Auto Rx in my 97 Subaru with 193k miles on it now. I'll do two treatments because of the high mileage. I did an oil analysis before adding, and will send out for oil analysis after the first and second treatment to see if anything changes. My mileage has also be lowering, so we'll see if that improves, too.
To be honest, with out a tear down there really is no way to know if you, me or any one even needs to use these products. It makes me feel good putting a bottle of the "good" stuff in there with the number of miles I have. Whether it is even necessary is highly debatable! With me, peace of mind always wins : )