I've had it with one job before (quick lube), but right now I would just be happy to have a regular paycheck, regardless of where it came from. I'm supposed to start work at one place next week, and should have already been working at another, but apparently there isn't enough work for me. They said that I'm hired, they just don't have anything for me to do. Great.
In the meantime, I'm doing odd jobs and hauling scrap metal. It sucks. Don't get me wrong, I love loading the truck up with metal and dumping it at the scrap yard for a few bucks, but finding enough metal (legally) to make a living off it is impossible. The odd jobs are not regular enough and high paying enough for me to make a living off them either.
My situation is somewhat affected by a legal issue I got myself into a few months ago. Had I not done that, I'd probably be fine as far as a job and finances right now, but I messed up, and I'm paying for it. If I knew my license wasn't in limbo, I'd apply anywhere, but now the commute is a big concern for me.
Keep in mind, it could always be worse. I have to tell myself that on a daily basis. If you can find something better, go for it, but don't give up your job for nothing. A paycheck is awesome, even if it sucks getting it.