Yes on the gasser T1X trucks with the 10L80, you have to pull the y-pipe at the exhaust manifolds. Pull the O2 sensors, unbolt the Y at the manifolds and drop the whole pipe to get enough clearance to get the pan off around I believe the transmission pump it is.
It honestly is an annoying job. 2/3 exhaust manifold studs on the passenger side pulled with the nuts and the nuts wouldn't budge (truck was only 10 months at the time). Ended up replacing them as they're just typical GM manifold studs.