On u-joints, always fill until grease comes out of all four ends. One might be clogged and the grease willl always flow through the easiest one first. Sometimes you need to move the car to change the angle so it will flow better. On others, as said above.
BUT, in industrial applications, motores, bearings, etc. Never put in more than needed to quiet the bearing. The more grease you add (past the right point) the higher the temperture of the bearing. A big problem we have here is that all the mechanics working in industry were once in charge of greasing trucks or cars.