Son has a 2006 Altima, 4cyl that I do some service on. Currently about 180,000 original everything except the catalytic converter, running synthetic oil every 6000-7000 OCIs since he got it with 58,000 miles on it. Have not considered HM oil as yet since no real oil consumption. transmission fluid has been a drain and fill every 30,000-40,000 with Amsoil ATF. Great vehicle