Will it make a significant difference over the life of the oil, probably no.
Is there are real difference, definitely yes.
A full synthetic 0W-20 is a great oil, just see Tig1's post above, but if we are here to split hairs (and most are) and it's above freezing and both oils are formulated the same, then the 5W20 does have better properties and they are measurable.
The oil formulator Joe believes there is a relation between sticking piston rings and oil volatility, with lower oil volatility being better.
Is there are real difference, definitely yes.
A full synthetic 0W-20 is a great oil, just see Tig1's post above, but if we are here to split hairs (and most are) and it's above freezing and both oils are formulated the same, then the 5W20 does have better properties and they are measurable.
The oil formulator Joe believes there is a relation between sticking piston rings and oil volatility, with lower oil volatility being better.