I had a cousin who saw some heavy, heavy action over in Vietnam. He came back...lets just say...mentally different than when he went over.
(Not directly related to my story, but...) Anyway, when he came back, he was a heavy chain smoker. He disappeared for a couple of decades and was living on the streets a thousand miles from his family, but when he finally decided he could live in the same vicinity as them, he got subsidized housing, an unlimited supply of smokes and managed to get a plain-jane '98 Ford Ranger. When he wasn't chain-smoking his cigs at home, he was chain-smoking his cigs in his Ranger.
I actually saw him about 10 minutes before he dropped dead from a heart attack about 15 years ago.
ANYWAY, his siblings parked the Ranger and it sat in a shed for about a year. I happened to see it and inquired about it and I got it for a song. Even though it had been sitting that long, when you opened the door, it reeked. My wife quickly reacquainted herself with a stick-shift on a deserted gravel road and drove it about six miles to our house. She got home and reeked of the smell. The next day was really windy here in the country and I parked the truck sideways, opened the doors, and I blew out several thousand cigarette butts. The smell was still there, so I gutted the falling head liner and hit it with as much deodorizer and neutralizer as I could.
It actually took months before you wouldn't be overpowered with the smell. Still, because we live in a rural area and my wife likes driving a manual transmission, it was one of her favorite vehicles, despite the frame eventually succumbing to rust.
I now own an electronic ozone generator. I wish I had it back then.