I work in the rubber elastomer sealing business, and when I hear seal swelling, I think of a seal that is being compromised, or degraded, and will be failing shortly. In the short run, it may be stopping a leak, as it is filling in a greater area. A torn seal or a worn sealing surface will be fixed temporarily. But the seal will need replacing eventually, and the sealing surface checked for wear. I think it would be unusual for a seal to be exposed to anything in or on an engine to cause it to swell, or degrade, but of course anything can happen.
As far as seal conditioning, as has been mentioned with doing an Auto-RX treatment, there is no swelling. Instead, the sludge creating a false seal is cleaned/removed, exposing the actual seal to to the conditioning elements of the oil. It is no longer "drying out", and hardening, from lack of oil. Seals need lubrication as much as bearings. The seal then is able to reconform by returning back to its original softness/hardness. This is a durometer measurement. Now, if the false sludge seal is covering a tear or a damaged or brittle seal, obviously there would be a leak problem.
One of the side benefits of some of the products mentioned on this board, in their maintenance doses, is to allow a seal to conform or stay conformed, in additional to keeping things clean.