I used DuraCool for several years in an old Thermo King Super reefer unit off a semi that we used to cool/heat our shop. It mixed readily with R12, cooled awesome, and we never once had any problems with the unit's cooling system. The diesel motor finally became unreliable with 36,000 hours on it and I got rid of it, but pulled the still good compressor, starter, etc. off of it and sold them to a guy with the same model. I did the charging myself and saved me a lot of money over the course of running that machine, since it held 15# of R12 and needed about 2-5# added every spring.