Generally, the higher the treadwear rating, the longer the tire lasts, AND, the harder the tire rides. Make sure you are going to be comfortable with your new tires. I go for less treadwear and a more comfortable ride. .02
Ironically-pure performance tires wear quickly and are likely harsher from a ride standpoint. Performance tires that last longer seem to have relatively better rides that outright performance tires that wear quickly. I imagine it may depend on the category of tires that are being compared and there are likely other factors that determine ride comfort… I remember driving on great fuel mileage low rolling resistance tires that wore faster and exhibited a harsher ride compared with non-fuel economy tires that lasted longer, got worse fuel economy, but had a better ride quality.