I know that I had never considered it before until I saw it on my 2006 used car purchased in 2016, where the spare had never been used. ........
Hot diggity dog! A variation of "dots on tires"!
There is very little commonality on marking wheels for high/heavy spots.
There is very little commonality on marking tires for high/heavy spots.
That's because each vehicle manufacturer has its own requirements and they don't seem to care what others are doing - they each do their own thing. BTW, each OEM requires some sort of marking so the tires can be match mounted to the wheels.
Also each wheel and tire manufacturer has to comply with the OEM requirements - and since those are all different, they are different as well - and some don't mark at all!! (except for what they supply to an OEM.)
You will - obviously - find marks on tires that match up with marks on wheels, but there doesn't seem to be a pattern.
Except to say that using a red dot on the tire for the high point is the most common of all of these marks. Next most common is using a yellow dot to indicate the heavy point of the tire. Beyond that, there is very little commonality.
It does not harm to match up the red dot on the tire with the valve hole, but it more often than not doesn't do any good.
Lastly, it doesn't matter how little or how much weight it takes to balance a tire/wheel assembly, once it is balanced, it's balanced. Reorienting the tire relative to the wheels changes where the weights need to go, but once it's balanced, it's balanced.