I ran an E50 blend in my '97 Grand Prix, and my Long Term Fuel Trim stayed right around +14.6%. It went like a rocket...considerably more power than straight gas, but MPG was horrible...I only got about 12 MPG on that tank compared to the nearly 30 it would get usually.
I used to run E20 in it all the time with no issues. LTFT was ~+4.5% on E20, and close to 0 on E10. Straight gas put it ~-2.7%
I expirimented with this for a while when they built the first E85 station close to me. They served up 3 different blends...E85, E20, and E10. For a while, they were saying E20 was okay to use in anything, but now there's a sticker on the pump saying it's for FFVs only. The guy I talked to said it's more of an EPA and warranty thing than any problems the cars might have.
I know I didn't have any problems...E20 is 91 octane, and kept any knock down to a bare minimum, along with being 5-7 cents a gallon cheaper than E10.