While I did find it a really nice car, I felt that due to how it "wanted" to be driven (by way of revs and shifting) - I felt it would wear-out sooner than the less high-strung cars we were trying out. Now, some would differ with me, in their assessment - but however well balanced an engine is, all things being equal, the one that revs higher will typically wear out sooner. And in like manner, the flick-flick-flick shifter that encourages quick and numerous shifts... will ultimately pack it in sooner, due to this carefree (and frequent) use.
I have an '06 TSX 6MT. I bought it in 2008 with 10k miles. I have driven it like it wants to be driven. It gets redlined multiple times daily.

It has 273k on it right now, with no signs of slowing down. My commute is backroads, so it accelerates 0-60+ frequently. The only issue the car's had was the steering rack at 125k. It still has the original clutch, even.
Best car I've ever owned.