My 2000 F250 Lariat Crew cab, 4x4, 6.8L V10 has 220,000 miles. Original drive train. Always had Valvoline MaxLife 5w20 or 5w30. Uses a quart between changes. Regular Transmission oil changes also, 4R100.
Very good information from all. I have two, 2008 Hemi 5.7L in Ram And Chrysler Aspen; and 2010 Dodge Nitro With 3.7L V6; 2000 Ford Super Duty 250 4x4, 6.8 V10. All stock from factory.